✦ LIBER ✦

Interpretation of treatment outcome in the clinically node-negative neck in primary parotid carcinoma: A systematic review of the literature

✍ Scribed by Matthijs H. Valstar; Michiel W. M. van den Brekel; Ludwig E. Smeele

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 110 KB
Volume: 32
Category: Article
ISSN: 1043-3074
DOI: 10.1002/hed.21316

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Background

Critical evaluation of outcome of primary parotid carcinoma treatment is limited by pathologic diversity and low incidence numbers. Scientific evidence for the optimal management of the N0‐neck is scarce and was, therefore, investigated in a systematic literature review.

Methods

The articles included were published in English between 1997 and 2007 and describe populations with the definitive pathology, staging, and treatment. Of 1104 articles, 19 were selected, describing 2703 patients.

Results

Of eligible populations, 83% were clinically N0. Pathology reporting of elective lymph node dissection (ELND) had limitations, but 23% showed occult metastases. Regional recurrence occurred in 5% of patients.

Conclusion

The discrepancy between the relatively high percentage of occult metastases and reported low regional recurrence rates may indicate the efficacy of treatment, being either ELND or radiotherapy of the neck. Pooling, standardized collection, and reporting of data are essential in comparing outcomes in populations to determine optimal treatment. © 2009 Wiley Periodicals, Inc. Head Neck, 2010

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