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Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism

โœ Scribed by Dessaud, Eric; Yang, Lin Lin; Hill, Katy; Cox, Barny; Ulloa, Fausto; Ribeiro, Ana; Mynett, Anita; Novitch, Bennett G.; Briscoe, James

Book ID
109897067
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
492 KB
Volume
450
Category
Article
ISSN
0028-0836

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โœ Yasushi Saka; James C Smith ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› BioMed Central ๐ŸŒ English โš– 821 KB

## Background One way in which positional information is established during embryonic development is through the graded distribution of diffusible morphogens. Unfortunately, little is known about how cells interpret different concentrations of morphogen to activate different genes or how thresholds