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Interplay of tissue factor splice variants in thrombosis

โœ Scribed by C. Tieken; Y.W. van den Berg; E.M. de Kruijf; P.J.K. Kuppen; P.H. Reitsma; V.Y. Bogdanov; H.H. Versteeg


Book ID
117258549
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
70 KB
Volume
129
Category
Article
ISSN
0049-3848

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## Abstract Tissue factor (TF) is a transmembrane glycoprotein that serves as the prime initiator of blood coagulation and plays a critical role in thrombosis and hemostasis. In addition, a variety of tumor cells overexpress cellโ€surface TF, which appears to be important for tumor angiogenesis and