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Interplay of SOS induction, recombinant gene expression, and multimerization of plasmid vectors in Escherichia coli

✍ Scribed by Jeewon Lee; Hyung-Cheol Kim; Sung-Woo Kim; Seung Wook Kim; Suk In Hong; Young-Hoon Park


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
353 KB
Volume
80
Category
Article
ISSN
0006-3592

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The production of several non-related heterologous proteins in recombinant Escherichia coli cells promotes a significant transcription of recA and sfiA SOS DNA repair genes. The activation of the SOS system occurs when the expression of plasmid-encoded genes is directed by the strong lambda lytic pr