𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Interplay of Isoprenoid and Peptide Substrate Specificity in Protein Farnesyltransferase †

✍ Scribed by Reigard, Sarah A.; Zahn, Todd J.; Haworth, Kellie B.; Hicks, Katherine A.; Fierke, Carol A.; Gibbs, Richard A.


Book ID
126829313
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
244 KB
Volume
44
Category
Article
ISSN
0006-2960

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Advances in the development of farnesylt
✍ Wenli Yang; Keith Del Villar; Jun Urano; Hiroshi Mitsuzawa; Fuyuhiko Tamanoi 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 92 KB 👁 1 views

A variety of compounds that show promise in cancer chemotherapy and chemoprevention have been identified as farnesyltransferase inhibitors. These can be classified into mainly two different types of inhibitors, farnesyl diphosphate competitors and CAAX peptidomimetics. The former type acts by compet

Comparison of Substrate Specificities of
✍ M. Loog; M. Eller; P. Ekman; L. Engstrom; S. Eriksson; J. Jarv; U. Ragnarsson; R 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 430 KB

Peptides, obtained by gradual removal of amino acids from both ends of pEKRPSQRSKYL, and stereoisomeric nonapeptides KRPSQRAKY with one D-amino acid residue successively in each position, were tested as substrates for protein kinase A. All these compounds were phosphorylated but at quite different r