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Interphase detection of immunoglobulin heavy chain gene translocations with specific oncogene loci in 173 patients with B-cell lymphoma

โœ Scribed by Akiko Tamura; Ikuo Miura; Shinsuke Iida; Shohei Yokota; Shigeo Horiike; Kazuhiro Nishida; Hiroshi Fujii; Shigeo Nakamura; Masao Seto; Ryuzo Ueda; Masafumi Taniwaki


Book ID
114135106
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
213 KB
Volume
129
Category
Article
ISSN
0165-4608

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## BACKGROUND. The demonstration of the monoclonality of immunoglobulin heavy chain (IgH) gene rearrangement is an indispensable method for the diagnosis of B-cell lymphoma as well as histocytochemical analysis. For the detection of IgH gene rearrangement, the extraction of DNA from a homogenous c