The development and application of a procedure for interphase cytogenetics on brain tumor material is described. Nuclei isolated from freshly removed brain tumor tissue were investigated for chromosomal aberrations by nonradioactive in situ hybridization with a panel of chromosome-specific probes. T
Interphase cytogenetics for studying solid tumors
β Scribed by Hon Fong L. Mark
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 57 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0008-543X
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Karyotypic analysis by direct demonstration of DNA sequences in interphase nuclei has been termed interphase cytogenetics and can be applied to a wide variety of cellular material, including paraffin-embedded tissue, allowing detection of both numerical and structural chromosome aberrations. The pri