An advanced course on Tumor Biology will be offered in Cairo, Egypt, October 14-24,1995, under the sponsorship of the UICC Tumor Biology Program and the co-sponsorship of the National Cancer Institute. The course will consist of topical avant-garde lectures given in the mornings and laboratory technology instructions given in the afternoons. It will be co-chaired by Dr. R. Brentani and Dr. E. Mihich, Chairman and Vice-chairman of the Tumor Biology Program; Dr. M.R. Hamza, Dean of the National Cancer Institute; and Dr. A.M. Kamel, the Executive Secretary of the Course. The Course will provide cutting-edge information on the biology of tumor viruses, the mechanism of chemical carcinogenesis, the role of oncogenes and tumor suppressor genes in oncogenesis, the molecular mechanisms of gene expression and of the control of the cell cycle, the phenomena of receptor-ligand interactions and related signaling pathways as well as the role of cell adhesion molecules in signaling, the phenomena of differentiation and apoptosis, the mechanisms involved in tumor metastasis, the therapeutic potential of monoclonal antibodies and of immunomodulation. The laboratory exercises will be focused on methodologies utilized in investigations of phenomena discussed in the lectures, including flow cytometry and immunophenotyping technologies. The course is intended to provide an opportunity for advanced training to young researchers who have obtained a formal training and a doctoral degree and who wish to increase their knowledge in the molecular and cellular biology of tumors towards developing a modern research program in the laboratory they are affiliated with. Although not strictly required, passing a TOEFL exam with a satisfactory score is desirable for applicants with native languages other than English. A maximum of 20 students will be accepted based on their qualifications. The lecture component of the course will be open to interested scientists from the region. The deadline for submission of applicants is September 25, 1995. For further information contact the UICC at telephone number: (41) 22-809-1811; fax number: (41) 22-809-1810.