Comparison of Sinemet CR4 and standard S
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Dr. Joseph Jankovic; Kenneth Schwartz; Chris Vander Linden
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Article
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1989
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John Wiley and Sons
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English
โ 414 KB
Wearing-off' effect, the most common form of levodopa-induced fluctuations, seems to be related to the short plasma half-life of the drug. More sustained plasma levodopa levels may be achieved with a new controiledrelease formulation of carbidopdevodopa, Sinemet CR4. We studied 20 patients, 12 men a