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International seroepidemiology of adenovirus serotypes 5, 26, 35, and 48 in pediatric and adult populations

✍ Scribed by Dan H. Barouch; Sandra V. Kik; Gerrit J. Weverling; Rebecca Dilan; Sharon L. King; Lori F. Maxfield; Sarah Clark; David Ng’ang’a; Kara L. Brandariz; Peter Abbink; Faruk Sinangil; Guy de Bruyn; Glenda E. Gray; Surita Roux; Linda-Gail Bekker; Athmanundh Dilraj; Hannah Kibuuka; Merlin L. Robb; Nelson L. Michael; Omu Anzala; Pauli N. Amornkul; Jill Gilmour; John Hural; Susan P. Buchbinder; Michael S. Seaman; Raphael Dolin; Lindsey R. Baden; Angela Carville; Keith G. Mansfield; Maria G. Pau; Jaap Goudsmit

Book ID
116963852
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
986 KB
Volume
29
Category
Article
ISSN
0264-410X

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✍ Rajendra Pilankatta; Tanu Chawla; Navin Khanna; Sathyamangalam Swaminathan 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 149 KB 👁 1 views

## Abstract In vivo gene delivery using human adenovirus serotype 5 (AdV5) vectors is being explored for vaccination purposes. The presence of anti‐AdV5 antibodies in human serum arising from natural exposure to AdV5 can interfere potentially with and compromise the efficacy of rAdV5‐based vaccine