𝔖 Bobbio Scriptorium
✦   LIBER   ✦

[International Review of Neurobiology] Basic Aspects of Catechol-O-Methyltransferase and the Clinical Applications of its Inhibitors Volume 95 || Catechol-O-Methyltransferase Enzyme

✍ Scribed by Müller, Thomas


Book ID
121335496
Publisher
Elsevier
Year
2010
Weight
617 KB
Category
Article
ISBN
0123813263

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Catechol-O-methyltransferase inhibitors:
✍ Jasper Dingemanse 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 305 KB 👁 2 views

Substitution therapy with levodopa and a peripheral inhibitor of aromatic L-amino acid decarboxylase (AADC) is the cornerstone in the treatment of Parkinson's disease. Chronic therapy with levodopa, however, is associated with the occurrence of motor complications that are partially related to the p

Synthesis and Biological Evaluation of P
✍ Ralph Paulini; Christian Lerner; François Diederich; Roland Jakob-Roetne; Gerhar 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 German ⚖ 431 KB

Inhibition of the enzyme catechol O-methyltransferase (COMT) represents a viable strategy for regulation of the catabolism of catecholamine neurotransmitters or their precursors, and is of considerable interest in the therapy of Parkinsons disease. Herein, we report the development of a new generati