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Internalizing antibodies and targeted cancer therapy: direct selection from phage display libraries

✍ Scribed by Ulrik B. Nielsen; James D. Marks

Book ID: 114401905
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 253 KB
Volume: 3
Category: Article
ISSN: 1461-5347
DOI: 10.1016/s1461-5347(00)00280-7

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## Abstract Compelling evidence suggests that vascular endothelial growth factor (VEGF) and its receptors play an important role in angiogenesis associated with tumor growth and metastasis. VEGF exerts its biologic activities through 2 transmembrane tyrosine kinase receptors: the __fms__‐like tyros