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Internalization of radioiodinated erythropoietin and the ligand-induced modulation of its receptor in murine erythroleukemia cells

โœ Scribed by Hiromi Fukamachi; Arinobu Tojo; Tsunehiro Saito; Toshio Kitamura; Akio Urabe; Fumimaro Takaku; Munetaka Nakata

Book ID
112212129
Publisher
AlphaMed Press
Year
1987
Tongue
English
Weight
788 KB
Volume
5
Category
Article
ISSN
1066-5099

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## Abstract We previously demonstrated that caspase-3, an executioner of apoptosis, is activated in the pressure-induced apoptosis of murine erythroleukemia (MEL) cells (at 100 MPa). Here, we examined the pathway of caspase-3 activation using peptide substrates and caspase inhibitors. Using the sub