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Internalization and intracellular sorting of the EGF receptor: a model for understanding the mechanisms of receptor trafficking

โœ Scribed by Madshus, I. H.; Stang, E.


Book ID
120230754
Publisher
The Company of Biologists Ltd
Year
2009
Tongue
English
Weight
395 KB
Volume
122
Category
Article
ISSN
0021-9533

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Epidermal growth factor (EGF) induces the degradation of EGF receptors in both human foreskin fibroblasts and A-431 cells. Similar degradation products of 125I-EGF covalently linked to its receptor appeared at the same times in both A-431 cells and fibroblasts when the cells were exposed to a concen