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Internal pilots for observational studies

✍ Scribed by Matthew J. Gurka; Christopher S. Coffey; Kelly K. Gurka


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
166 KB
Volume
52
Category
Article
ISSN
0323-3847

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πŸ“œ SIMILAR VOLUMES


A METHOD FOR DETERMINING THE SIZE OF INT
✍ LEIV SANDVIK; JAN ERIKSSEN; PETTER MOWINCKEL; EINAR ANDREAS RØDLAND πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 266 KB πŸ‘ 3 views

The assessment of sample size in clinical trials comparing population means requires a variance estimate of the main efficacy variable. When this variance estimate has a low precision, it may be appropriate to use the data from the first patients entered in the trial ('internal pilot study') to esti

Internal pilot studies II: comparison of
✍ David M. Zucker; Janet T. Wittes; Oliver Schabenberger; Erica Brittain πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 121 KB πŸ‘ 2 views

The two-stage design involves sample size recalculation using an interim variance estimate. Stein proposed the design in 1945; biostatisticians recently have shown renewed interest in it. Wittes and Brittain proposed a modiΓΏcation aimed at greater e ciency; Gould and Shih proposed a similar procedur

Some Aspects of the Application of Inter
✍ Peter A. Lachenbruch; Janet Wittes πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 46 KB πŸ‘ 2 views

## Abstract This is a discussion of the paper' Sample size recalculation in internal pilot study designs' by Tim Friede and Meinhard Kieser, appearing in this special issue on adaptive designs. (Β© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)