Internal inversion used to study regulation of the int gene in bacteriophage λ
✍ Scribed by OPPENHEIM, AMOS B.
- Book ID
- 109699581
- Publisher
- Nature Publishing Group
- Year
- 1976
- Tongue
- English
- Weight
- 236 KB
- Volume
- 261
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/261615a0
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The activation of the int gene by the cII and cIII gene products was studied by analysing int expression following infection of UV-irradiated cells by various phage mutants. Residual expression of int, probably from Pl, takes place in the absence of cII/cIII activation. Activation of the int gene, l
The location of 14 independently isolated spontaneous pi A and pi B point mutants in the lambda P gene and their base exchanges were determined. It was found that the pi B mutation is one unique type mapping close to other pi A mutants. The number of possible pi A mutation sites could be estimated.