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Internal Cleavage of Hepatitis C Virus NS3 Protein Is Dependent on the Activity of NS34A Protease

โœ Scribed by Se-Hwan Yang; Chang Geun Lee; Man Ki Song; Young Chul Sung


Book ID
112272450
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
318 KB
Volume
268
Category
Article
ISSN
0042-6822

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HCV reoccurs after liver transplantation and increases mortality. Cyclosporine, but not tacrolimus, has potent antiviral effects against HCV replication in cell culture. To determine the conditions, if any, under which HCV is susceptible to cyclosporine in vivo, we selected for cyclosporine-resistan