Intermittent treatment with human parathyroid hormone (1-34) ] stimulates bone formation and increases cancellous bone mass in ovariectomized (OW) rats. But PTH-induced cancellous bone rapidly disappears upon cessation of treatment. The fate of cortical bone treated by PTH has not been well characte
✦ LIBER ✦
Intermittent Fugu parathyroid hormone 1 (1–34) is an anabolic bone agent in young male rats and osteopenic ovariectomized rats
✍ Scribed by Julie F. McManus; Rachel A. Davey; Helen E. MacLean; Elizabeth A. Doust; W.S. Maria Chiu; Natalie A. Sims; Mary L. Bouxsein; Vaida Glatt; Jeffrey D. Zajac; Janine A. Danks
- Book ID
- 116320602
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 1004 KB
- Volume
- 42
- Category
- Article
- ISSN
- 8756-3282
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To evaluate the potential use of a combination of parathyroid hormone (PTH) and estrogen as therapy for osteoporosis, we examined the effects of combined and separate administration of low-dose PTH and estradiol in ovariectomized rats with established osteopenia. Ovariectomized rats were untreated f