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Intermittent and continuous exposure to 1,25(OH)2D3 have different effects on growth plate chondrocytes in vitro

✍ Scribed by Klaus, Günter; König, Birgit; Hügel, Ulrike; Ritz, Eberhard; Mehls, Otto

Book ID
109882505
Publisher
Nature Publishing Group
Year
1993
Tongue
English
Weight
775 KB
Volume
44
Category
Article
ISSN
0085-2538

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Recent studies have shown that 24R,25-(OH) 2 D 3 mediates its effects on growth plate chondrocytes via membrane receptors. This study examined the roles of phospholipase A 2 (PLA 2 ) and cyclooxygenase (Cox) in the mechanism of action of 24R,25-(OH) 2 D 3 in resting zone chondrocytes in order to det