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Intermedin and the unfolded protein response

✍ Scribed by Friedrich C. Luft

Publisher: Springer
Year: 2011
Tongue: English
Weight: 127 KB
Volume: 89
Category: Article
ISSN: 0946-2716
DOI: 10.1007/s00109-011-0827-2

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## Abstract Cancer cells in poorly vascularized solid tumors are constantly or intermittently exposed to stressful microenvironments, including glucose deprivation, hypoxia, and other forms of nutrient starvation. These tumor‐specific conditions, especially glucose deprivation, activate a signaling