Intermediates in the Paal-Knorr Synthesis of Pyrroles. 4-Oxoaldehydes
β Scribed by Amarnath, Venkataraman; Amarnath, Kalyani; Valentine, William M.; Eng, Michael A.; Graham, Doyle G.
- Book ID
- 120809102
- Publisher
- American Chemical Society
- Year
- 1995
- Tongue
- English
- Weight
- 613 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0893-228X
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π SIMILAR VOLUMES
Treatment of 1,4-diketones with liquid ammonia gives high yields of isolable 2-hydroxy-3,4-dihydro-ZH-pyrrole intermediates. These intermediates, which do not appear to have been observed previously in the ?aal-norr s have been fully characterized by i-r. r and Hand nthesis with anaaonia, C n.m.r. s
## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract Fully substituted pyrrolβ3βol derivatives (V) are prepared via aldol reactions of propaneβ2βone with phenylglyoxal followed by PaalβKnorr reaction with amines.