𝔖 Bobbio Scriptorium
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Intermediates in the enzymic synthesis of tetrahydrobiopterin in Drosophila melanogaster

✍ Scribed by Arthur C. Switchenko; Jann P. Primus; Gene M. Brown

Book ID
117056481
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
352 KB
Volume
120
Category
Article
ISSN
0006-291X

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Annotation of the sequenced Drosophila genome suggested the presence of an additional enzyme with extensive homology to mammalian tryptophan hydroxylase, which we have termed DTRH. In this work, we show that enzymatic analyses of the putative DTRH enzyme expressed in Escherichia coli confirm that it