Intermediary Metabolism in HeLa and Human Foetal Liver Cells
β Scribed by Bryant, C; Smith, M J H
- Book ID
- 109832928
- Publisher
- Nature Publishing Group
- Year
- 1963
- Tongue
- English
- Weight
- 595 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0007-0920
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## Abstract The highest concentration of 9βhydroxybenfluron (HBF) tested, namely 4Β·05 ΞΌmol1^β1^, induced immediate cytotoxic effects which were manifested by total inhibition of cell proliferation after only 24 h of culture. In a certain proportion of the cells cytolytic effects were observed at lo
Incubation of HeLa cells at 42Β°C results in pronounced inhibition of the accumulation of 18s and 28s ribosomal RNA (rRNA) and non-heat shock polyadenylated messenger RNA (mRNA) in the cytoplasm. Accumulation of transfer RNA and 5s ribosomal RNA is not affected. Transcription of rRNA precursor is red