Interleukin-7, interleukin-12, and GM-CSF gene transfer in patients with metastatic melanoma
β Scribed by D. Schadendorf; B. M. Czarnetzki; B. Wittig
- Book ID
- 104661594
- Publisher
- Springer
- Year
- 1995
- Tongue
- English
- Weight
- 441 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0946-2716
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## BACKGROUND. Interleukin-2 (IL-2) has been used widely in the treatment of advanced melanoma, most often using a high dose bolus schedule of administration. We have evaluated the antitumor activity and toxicity of IL-2 when administered by a continuous infusion schedule in patients with metastat
## Abstract ## BACKGROUND Interleukinβ2 (ILβ2) has activity in metastatic melanoma when given in high doses by the intravenous (IV) route, but its side effects and effectiveness when given in intermediate to high doses by the subcutaneous (SC) route have not been studied adequately. This study sou