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Interleukin-6, vascular endothelial growth factor and transforming growth factor beta 1 in canine steroid responsive meningitis-arteritis

✍ Scribed by Arianna Maiolini, Meike Otten, Marion Hewicker-Trautwein…


Book ID
120684453
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
324 KB
Volume
9
Category
Article
ISSN
1746-6148

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## Abstract VEGF and TGF‐β1 induce angiogenesis but have opposing effects on endothelial cells. VEGF protects endothelial cells from apoptosis; TGF‐β1 induces apoptosis. We have previously shown that VEGF/VEGF receptor‐2 (VEGFR2) signaling mediates TGF‐β1 induction of apoptosis. This finding raised