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Interleukin-6 promoter variants, prostate cancer risk, and survival

✍ Scribed by Elizabeth A. Tindall; Gianluca Severi; Hoa N. Hoang; Melissa C. Southey; Dallas R. English; John L. Hopper; Graham G. Giles; Vanessa M. Hayes; Australian Prostate Cancer BioResource

Book ID
112179682
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
135 KB
Volume
72
Category
Article
ISSN
0270-4137

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## Abstract Interleukin‐6 (IL6) is a growth and survival factor in human prostate cancer (PCa) cells with aggressive phenotypes and has been implicated in the progression of hormone refractory PCas. In the present study, we characterized the IL6‐triggered PI3K/Akt and MAPK/Erk signaling. We identif