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Interleukin-6 modulates trabecular and endochondral bone turnover in the nude mouse by stimulating osteoclast differentiation

โœ Scribed by N Rozen; S Ish-Shalom; A Rachmiel; H Stein; D Lewinson

Book ID
117806948
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
835 KB
Volume
26
Category
Article
ISSN
8756-3282

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The cytokine interleukin-6 (IL-6) was produced by neonatal mouse parietal bones during a 6- or 48-hour culture period in response to prostaglandin E2 (PGE2) and bovine parathyroid hormone (PTH) 1-34 fragment but not 1,25-dihydroxyvitamin D3 [1,25(OH)2D3]. At the same time there was an increase in ta