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Interleukin-6 does not stimulate bone resorption in neonatal mouse calvariae

✍ Scribed by Abdulkarim Al-Humidan; Stuart H. Ralston; David E. Hughes; Karen Chapman; Lucien Aarden; R. Graham G. Russell; Dr. Maxine Gowen

Book ID
112118674
Publisher
American Society for Bone and Mineral Research
Year
2009
Tongue
English
Weight
407 KB
Volume
6
Category
Article
ISSN
0884-0431

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Interleukin-1 (IL-1) is probably an important lymphokine mediator of inflammation and bone resorption. IL-1 derived from mononuclear cells, a melanoma cell line (MM96 cells), and recombinant human IL-1 (rHuIL-1 beta) increased in vitro bone resorption, as measured by the release of 45Ca from culture