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Interleukin-4 distinctively modifies responses of germinal centre-like and activated B-cell-like diffuse large B-cell lymphomas to immuno-chemotherapy

โœ Scribed by Kristopher A. Sarosiek; Hovav Nechushtan; Xiaoqing Lu; Joseph D. Rosenblatt; Izidore S. Lossos


Book ID
108676455
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
476 KB
Volume
147
Category
Article
ISSN
0007-1048

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## Abstract Diffuse large B cell lymphoma (DLBCL) is an aggressive malignancy that accounts for nearly 40% of all lymphoid tumors. This heterogeneous disease can be divided into germinal center B cellโ€like (GCB) and activated B cellโ€like (ABC) subtypes by gene expression and immunohistochemical pro