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Interleukin-28B (IL-28B) single-nucleotide polymorphisms and interferon plus ribavirin treatment outcome in Italian chronically HCV-infected patients

โœ Scribed by E. Riva; C. Scagnolari; K. Monteleone; C. Selvaggi; A. Picardi; C. Mazzarelli; E. Pizzigallo; B. Vincenzi; A. Carducci; S. Antonaci; G. Giannelli; G. Antonelli


Book ID
117947775
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
166 KB
Volume
19
Category
Article
ISSN
1352-0504

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Single nucleotide polymorphisms (SNPs) near the interleukin 28B (IL28B) region are the strongest baseline predictors of a sustained virologic response (SVR) to peg-interferon (PegIFN) and ribavirin (Rbv) in patients with hepatitis C virus (HCV) genotype 1 infection. Whether this holds true for HCV-4

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We read with great interest the recent report by Li et al. 1 analyzing the correlation between the clusters of differentiation 24 (CD24) polymorphism and risk of chronic hepatitis B virus (HBV) infection. In their study, the CD24 P170 T allele (thymidine at position 170) was correlated with a strong