Interleukin-28B genetic variants in identification of hepatitis C virus genotype 1 patients responding to 24 weeks peginterferon/ribavirin
β Scribed by Chung-Feng Huang; Jee-Fu Huang; Jeng-Fu Yang; Ming-Yen Hsieh; Zu-Yau Lin; Shinn-Cherng Chen; Liang-Yen Wang; Suh-Hang Hank Juo; Ku-Chung Chen; Wan-Long Chuang; Hsing-Tao Kuo; Chia-Yen Dai; Ming-Lung Yu
- Book ID
- 116652470
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 639 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0168-8278
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Approximately one third of hepatitis C virus (HCV) genotype 1 patients achieved a sustained virological response (SVR) after 24 weeks of treatment with peginterferon alpha-2a (40 kd) plus ribavirin in a randomized, multinational trial. We aimed to identify factors associated with a rapid virological
## Abstract The course and outcome in patients infected with hepatitis C virus (HCV) genotype 1b with partial early virologic response during combination therapy with peginterferon and ribavirin, in whom serum HCV RNA is detectable but has decreased by more than 2βlog~10~ 12 weeks after the start o
## Abstract Variation at the ILβ28B locus was recently reported to be a significant predictive factor of viral response to pegylatedβinterferon plus ribavirin combination therapy against chronic hepatitis C. Predictive factors for the effect of therapy, including ILβ28B polymorphism rs8099917 and v
## Abstract For chronic hepatitis C virus (HCV) infection, evaluation of response to peginterferon (PEGβIFN) plus ribavirin (RBV) therapy based on viral kinetics is useful as an early predictor of treatment efficacy, but the underlying mechanisms of the different viral kinetics to treatment are sti