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Interleukin-27 upregulates major histocompatibility complex class II expression in primary human endothelial cells through induction of major histocompatibility complex class II transactivator

✍ Scribed by Xiao Ming Feng; Xiao Li Chen; Na Liu; Zhong Chen; Yu Ling Zhou; Zhi Bo Han; Lei Zhang; Zhong Chao Han


Book ID
116531773
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
747 KB
Volume
68
Category
Article
ISSN
0198-8859

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We analyzed whether normal human hepatocytes, which normally do not display Class I1 major histocompatibility complex antigens, can be induced to express them in vitro, and whether this induction has an in vivo counterpart in chronic liver diseases. While both a-and y-interferon induced expression o