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Interleukin-2 receptors and interleukin-2-mediated signaling in myelin: activation of diacylglycerol kinase and phosphatidylinositol 3-kinase

✍ Scribed by G Chakraborty; R Reddy; A Drivas; R.W Ledeen


Book ID
116786085
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
214 KB
Volume
122
Category
Article
ISSN
0306-4522

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Interleukin-2 induces a serine-phosphorylated phosphatidylinositol 3 kinase activity in the mouse T cell line TSlaP. Moreover, protein kinase C (PKC) directly or indirectly associates with the phosphatidylinositol 3 kinase and the association appears to be necessary for the serine-phosphorylated pho