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Interleukin-1β promotes oligodendrocyte death through glutamate excitotoxicity

✍ Scribed by Jennifer L. Takahashi; Fabrizio Giuliani; Christopher Power; Yoshinori Imai; V. Wee Yong

Book ID
101465059
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
275 KB
Volume
53
Category
Article
ISSN
0364-5134

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✍ Victoria Louise Pearson; Nancy Jane Rothwell; Sylvie Toulmond 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 552 KB

Interleukin-1 beta (IL-1␤) has been proposed as a mediator of several forms of brain damage, including that induced by excitotoxins. In vitro studies suggest that glial cells are the effector cells of IL-1␤-mediated neurodegeneration. We have investigated the expression of IL-1␤ protein by glial cel