Heat shock alters Alzheimer's β amyloid
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J. R. Ciallella; V. V. Rangnekar; Ph.D. J. P. McGillis
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Article
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1994
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John Wiley and Sons
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English
⚖ 847 KB
One of the pathological lesions in Alzheimer's disease (AD) is the amyloid or senile plaque. The plaque core is predominantly made up of amyloid beta peptide (AP), a 42-43 amino acid peptide derived from amyloid precursor protein (APP). APP is a membrane bound glycoprotein which is expressed ubiquit