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Interleukin-1α stimulates interstitial collagenase gene expression in human dental pulp fibroblast

✍ Scribed by Masato Tamura; Shigetaka Nagaoka; Masataka Kawagoe

Book ID: 117273427
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 471 KB
Volume: 22
Category: Article
ISSN: 0099-2399
DOI: 10.1016/s0099-2399(06)80140-8

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## ) is a potent cytokine that stimulates interstitial collagenase-1 (matrix metalloproteinase-1; MMP-1). In this study, we compared the mechanism(s) by which IL-1b induces collagenase gene expression in two very different cells, normal human foreskin fibroblasts (HFFs) and an aggressive breast ca