Interleukin-1α induction of tensile weakening associated with collagen degradation in bovine articular cartilage

Retinoic acid combines with interleukin-

Retinoic acid combines with interleukin-1 to promote the degradation of collagen from bovine nasal cartilage: Matrix metalloproteinases-1 and -13 are involved in cartilage collagen breakdown

✍ W.D. Shingleton; A.J. Ellis; A.D. Rowan; T.E. Cawston 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 237 KB 👁 2 views

Retinoic acid (RetA) and interleukin-1␣ (IL-1) together can induce a reproducible release of proteoglycan fragments from bovine nasal cartilage in culture. However, release of collagen fragments with either agent alone is often variable. In this study over 70% of the total collagen was released from