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Interleukin-18 induces the production of vascular endothelial growth factor (VEGF) in rheumatoid arthritis synovial fibroblasts via AP-1-dependent pathways

✍ Scribed by Mi-La Cho; Young Ok Jung; Young-Mi Moon; So-Youn Min; Chong-Hyeon Yoon; Sang-Heon Lee; Sung-Hwan Park; Chul-Soo Cho; Dae-Myung Jue; Ho-Youn Kim

Book ID: 108152278
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 314 KB
Volume: 103
Category: Article
ISSN: 0165-2478
DOI: 10.1016/j.imlet.2005.10.020

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## Abstract ## Objective To examine the role of interferon regulatory factor 1 (IRF‐1) in tumor necrosis factor α (TNFα)–induced interleukin‐18 binding protein a (IL‐18BPa) expression in rheumatoid arthritis synovial fibroblasts (RASFs). ## Methods TNFα‐induced IRF‐1 expression was assessed by r