Interleukin-18/WNT1-inducible signaling
โ
Venkatapuram Seenu Reddy; Anthony J. Valente; Patrice Delafontaine; Bysani Chand
๐
Article
๐
2011
๐
John Wiley and Sons
๐
English
โ 737 KB
We demonstrate for the first time that the pro-inflammatory cytokine interleukin (IL)-18 stimulates rapid and significant proliferation of SMC derived from human saphenous vein (VSMC), but not coronary artery. IL-18 also stimulates VSMC growth. Further investigations revealed that IL-18-induced VSMC