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Interleukin 18 (IL-18) Regulates Human Saphenous Vein Smooth Muscle Cell Function

โœ Scribed by Patel, P.; Gurav, A.; Chun, M.; LoGerfo, F.W.; Nabzdyk, L. Pradhan


Book ID
122060196
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
148 KB
Volume
179
Category
Article
ISSN
0022-4804

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Interleukin-18/WNT1-inducible signaling
โœ Venkatapuram Seenu Reddy; Anthony J. Valente; Patrice Delafontaine; Bysani Chand ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 737 KB

We demonstrate for the first time that the pro-inflammatory cytokine interleukin (IL)-18 stimulates rapid and significant proliferation of SMC derived from human saphenous vein (VSMC), but not coronary artery. IL-18 also stimulates VSMC growth. Further investigations revealed that IL-18-induced VSMC