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Interleukin-17+CD8+ T Cells Are Enriched in the Joints of Patients With Psoriatic Arthritis and Correlate With Disease Activity and Joint Damage Progression

✍ Scribed by Menon, Bina; Gullick, Nicola J.; Walter, Gina J.; Rajasekhar, Megha; Garrood, Toby; Evans, Hayley G.; Taams, Leonie S.; Kirkham, Bruce W.


Book ID
121729795
Publisher
Wiley (John Wiley & Sons)
Year
2014
Tongue
English
Weight
912 KB
Volume
66
Category
Article
ISSN
2326-5191

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Interleukin-17+CD8+ T Cells Are Enriched
✍ Menon, Bina; Gullick, Nicola J.; Walter, Gina J.; Rajasekhar, Megha; Garrood, To πŸ“‚ Article πŸ“… 2014 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 912 KB

## Objective Psoriatic arthritis (PsA) is associated with HLA class I genes, in contrast to the association with HLA class II in rheumatoid arthritis (RA). Since IL-17+ cells are considered important mediators of synovial inflammation, we sought to determine whether IL-17–producing CD8+ T cells may