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Interleukin-17 up-regulation of nitric oxide production in human osteoarthritis cartilage

✍ Scribed by Mukundan G. Attur; Rajesh N. Patel; Steven B. Abramson; Ashok R. Amin

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 339 KB
Volume: 40
Category: Article
ISSN: 0004-3591
DOI: 10.1002/art.1780400609

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## Abstract ## Objective Stromal cell–derived factor 1 (SDF‐1) is a potent chemoattractant for memory T cells in inflamed rheumatoid arthritis (RA) synovium. This study was undertaken to investigate the effect of interleukin‐17 (IL‐17) and CD40–CD40L interaction on SDF‐1 production in RA fibroblas