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Interleukin 17 acts in synergy with B cell–activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus

✍ Scribed by Doreau, Agnès; Belot, Alexandre; Bastid, Jérémy; Riche, Benjamin; Trescol-Biemont, Marie-Claude; Ranchin, Bruno; Fabien, Nicole; Cochat, Pierre; Pouteil-Noble, Claire; Trolliet, Pierre


Book ID
109920789
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
587 KB
Volume
10
Category
Article
ISSN
1529-2908

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## Abstract It has recently been found that excessive serum B‐cell activating factor (BAFF) production triggers severe autoimmune disorders in mice resembling systemic lupus erythematosus (SLE). Whether such dysregulation in circulating levels of BAFF results from overexpression of BAFF gene in cli