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Interleukin-12 regulates the proliferation of Th1, but not Th2 or Th0, clones

✍ Scribed by Mary K. Kennedy; Kathleen S. Picha; Kurt D. Shanebeck; Dirk M. Anderson; Kenneth H. Grabstein


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
902 KB
Volume
24
Category
Article
ISSN
0014-2980

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The T1/ST2 gene encodes, as a result of differential splicing, a cell surface protein (transmembrane form of T1/ST2, ST2L) and a soluble, secreted, protein (ST2). Here, we show that transcripts for both ST2L and ST2 are present in activated human Th2 clones, but not in Th1 and T regulatory clones. T