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Interleukin-10–592C/A, –819C/T and –1082A/G promoter variants affect the susceptibility to nephropathy in Tunisian type 2 diabetes (T2DM) patients

✍ Scribed by Intissar Ezzidi; Nabil Mtiraoui; Maha Kacem; Samir G. Mallat; Manel Ben Hadj Mohamed; Molka Chaieb; Touhami Mahjoub; Wassim Y. Almawi

Book ID: 108704213
Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 120 KB
Volume: 70
Category: Article
ISSN: 0300-0664
DOI: 10.1111/j.1365-2265.2008.03337.x

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## Abstract ## Background The IL‐10 promoter polymorphisms ‐1082G/A, ‐819C/T, and ‐592C/A have been consistently associated with type 2 diabetes (T2DM). We examined whether these polymorphisms variants are also associated with progression of diabetic nephropathy (DN). ## Methods These promoter v