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Interleukin-10 promoter polymorphisms and the outcome of hepatitis C virus infection

โœ Scribed by Susanne Knapp; BranwenJ.W. Hennig; AngelaJ. Frodsham; Lyna Zhang; Simon Hellier; Mark Wright; Rob Goldin; AdrianV.S. Hill; HowardC. Thomas; MarkR. Thursz

Publisher
Springer-Verlag
Year
2003
Tongue
English
Weight
165 KB
Volume
55
Category
Article
ISSN
0093-7711

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Serum levels of interleukin-10 (IL-10) are elevated in a proportion of patients with untreated chronic hepatitis C, and this may compromise the host immune response to the virus. The capacity for IL-10 production varies according to the genetic composition of the IL-10 locus. We examined the inherit