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Interleukin-10 Production by Splenic CD4+ Cells and Cell Subsets from Young and Old Mice

✍ Scribed by Monte V. Hobbs; William O. Weigle; David N. Ernst


Book ID
112238917
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
320 KB
Volume
154
Category
Article
ISSN
0008-8749

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πŸ“œ SIMILAR VOLUMES


Cell proliferation and cytokine producti
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Splenocytes from young adult or old C57BUGNNia mice were stimulated in vitro with the anti-CD~E mAb, 145-2C11, in either soluble (2C11 s) or plate-bound (2C11 i) form. In the young group, each mode of cell activation resulted in peak DNA synthesis at -48 h of culture; at this time point, the old gro

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## Abstract There is a growing body of evidence which suggests that CD8^+^ T cells play an important part in regulating the IgE response to non‐replicating antigens. In this study we have systematically investigated their role in the regulation of IgE and of CD4^+^ T cell responses to ovalbumin (OV