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Interleukin-10 or tumor necrosis factor-α polymorphisms and the natural course of hepatitis C virus infection in a hyperendemic area of Japan

✍ Scribed by Kazunori Kusumoto; Hirofumi Uto; Katsuhiro Hayashi; Yuka Takahama; Hiroyuki Nakao; Robert Suruki; Sherri O. Stuver; Akio Ido; Hirohito Tsubouchi


Book ID
116397721
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
143 KB
Volume
34
Category
Article
ISSN
1043-4666

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## Abstract Cytokines play a key role in the regulation of immune responses. In hepatitis C virus infection (HCV), the production of inappropriate cytokine levels appears to contribute to viral persistence and to affect response to therapy. Cytokine genes are polymorphic at specific sites, and cert