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Interleukin 1 regulates the expression of osteopontin mRNA by osteoblasts

✍ Scribed by Cheng He Jin, ; Chisato, Miyaura; Yoshiko, Ishimi; Mei Hua Hong, ; Toshiyuki, Sato; Etsuko, Abe; Tatsuo, Suda

Book ID
123553046
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
782 KB
Volume
74
Category
Article
ISSN
0303-7207

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## Abstract Interleukin‐1 (IL‐1)Ξ± is an autocrine/paracrine agent of the skeletal tissue and it regulates bone remodeling. Collagenase‐3 or matrix metalloproteinase (MMP)‐13 is expressed in osteoblasts and its expression is modulated by several cytokines including IL‐1Ξ±. Because the molecular mecha