Coordinate production of interleukin-1 (3 (IL-1 (3) and granulocyte macrophagecolony stimulating factor (CM-CSF) or IL-6 by the blast cells of acute myeloblastic leukemia (AML) and normal peripheral blood leukocytes have been previously reported (van der Shoot et al.:
โฆ LIBER โฆ
Interleukin-1 is one factor which regulates autocrine production of GM-CSF by the blast cells of acute myeloblastic leukaemia
โ Scribed by D. Bradbury; S. Rogers; R. Kozlowski; G. Bowen; I. A. G. Reilly; N. H. Russell
- Book ID
- 114712286
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 530 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0007-1048
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The human leukemic cell line AML-193 was tested for its proliferative response to endogenously produced autocrine factors and to a variety of cytokines and colony-stimulating factors. Cells grown in the absence of GM-CSF incorporated tritiated thymidine, and this was partially reversed by adding neu