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Interleukin-1 induction by lipopolysaccharides: Structural requirements of the 3-deoxy-d-manno-2-octulosonic acid (KDO)

✍ Scribed by Nicole Haeffner-Cavaillon; Martine Caroff; Jean-Marc Cavaillon


Book ID
118384220
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
961 KB
Volume
26
Category
Article
ISSN
0161-5890

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Synthesis of trisaccharides containing 3
✍ Paul Kosma; Gerhard Schulz; Frank M. Unger; Helmut Brade πŸ“‚ Article πŸ“… 1989 πŸ› Elsevier Science 🌐 English βš– 749 KB

Glycosylation of methyl (ally1 7,8-0-carbonyl-3-deoxy-a-D-manno-2-octulopyranosid)onate with an (w-(2+4) linked per-0-acetylated KDO-disaccharide bromide derivative under Helferich conditions afforded a 2: 1 mixture of the (Y-and p-linked trisaccharide derivatives in 50% yield. Removal of the protec